Gakpo’s injury adds to Liverpool’s woes after Alexander Isak withdrew from Sweden duty with a minor thigh injury.
The striker played the full 90 minutes and scored a goal in his side’s 2-1 win on Friday over Romania in the Nations League.
However, he will not be involved in Sweden’s remaining three matches in this international break and assessed by his club’s medical staff.
On Thursday, Arsenal forward Kai Havertz and Sunderland’s Brian Brobbey both went off injured in the same game as the Netherlands drew with Germany.
German Havertz was caught on the knee by a high boot from Quinten Timber in Amsterdam and had to be replaced.
Netherlands forward Brobbey – off the back off a hat-trick in Sunderland’s 5-3 Premier League defeat by Manchester City – then appeared to suffer a muscle injury.
A further blow for Sunderland on this international break came as Dan Ballard suffered a hamstring injury late in Northern Ireland’s 1-0 win over Georgia on Friday.
Boss Michael O’Neill has confirmed the injury will rule him out of the national team’s remaining fixtures in this international break.
It is not just Premier League teams who are being impacted by injuries to their players while on international duty.
Real Madrid striker Kylian Mbappe has been ruled out for at least two weeks after injuring his knee while scoring the winner in Zinedine Zidane’s first game in charge of France.
He scored a record-extending 67th goal from Michael Olise’s pass to sink Turkey, but he was limping immediately and had to be replaced five minutes later.
Meanwhile, Bayern Munich’s Jamal Musiala suffered a muscle injury during the warm-up for the game against the Netherlands and had to withdraw.
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